yes i take peptides · shopping companion

SS-31 (Elamipretide)

Forzinity / SS-31

Category · For LongStatus · FDACitations · 60

The verdict

Yes for trial-eligible mitochondrial disease patients — no for healthy-adult longevity use.

By source — cost, legality, risk

Brand — Forzinity (Stealth Biotherapeutics)
~$200,000+/year via specialty pharmacy
FDA-approved Sept 2025 · Barth syndrome only
Lowest molecular. Ultra-rare-disease pricing; only realistic for diagnosed Barth patients with insurance coverage.
Compounded 503A pharmacy
Not meaningfully available
Not available — no 503A path post-approval
Post-approval, 503A compounding is closed; brand or RUO are the only realistic channels.
RUO research peptide
$80–$300/mo at community 1–4mg/d
Sold 'for research only'
Highest. The D-amino acid stereochemistry matters for activity; RUO product made with all-L is a different molecule. Chiral HPLC rarely run.
Gray-market raw
$25–$125/mo
Unregulated overseas import
Crypto/Wise pay; same D-stereochemistry concern as RUO; identity verification by mass spec alone is insufficient.

Stop signals · abort if

Sources · top 5 of 60

01Zhao W, et al. Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice. Journal of neuroinflammation. 2019;16(1):230. PMID: 31747905.
02Zheng H, et al. SS-31@Fer-1 Alleviates ferroptosis in hypoxia/reoxygenation cardiomyocytes via mitochondrial targeting. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2025;183:117832. PMID: 39848110.
03Nie Y, et al. Elamipretide(SS-31) Attenuates Idiopathic Pulmonary Fibrosis by Inhibiting the Nrf2-Dependent NLRP3 Inflammasome in Macrophages. Antioxidants (Basel, Switzerland). 2023;12(12). PMID: 38136142.
04Whitson JA, et al. Elamipretide (SS-31) treatment attenuates age-associated post-translational modifications of heart proteins. GeroScience. 2021;43(5):2395-2412. PMID: 34480713.
05Tung C, et al. Elamipretide: A Review of Its Structure, Mechanism of Action, and Therapeutic Potential. International journal of molecular sciences. 2025;26(3). PMID: 39940712.