yes i take peptides · shopping companion
NAD+
Category · For LongStatus · OTCCitations · 60
The verdict
Mostly no for IV — depends for oral, and "depends" leans no.
By source — cost, legality, risk
- BrandNot availableNone — no FDA-approved injectable NAD+No FDA-approved injectable NAD+. Oral NR / NMN are a different molecule sold OTC as supplements — covered in the tldr, not on this grid.
- Compounded 503A pharmacy (IV-drip clinic OR tele-clinic subq)$200–$1,500/mo depending on routeRx · IV at $300–$1,500/session, subq at $200–$400/mo via tele-clinicMid for tele-clinic subq; markup-heavy for IV-drip 'loading' protocols (no clinical evidence for 5–10-session patterns at sold doses). Burning at subq injection site is the molecule, not contamination.
- RUO injectable$60–$200/mo (community dose patterns vary widely)Sold 'for research only'Highest. Pre-mixed product older than 30 days is sub-potent (NAD+ degrades in solution).
- Gray-market rawVaries — not on user's gray-vendor list 2026Unregulated overseas importUnverified. NAD+ degrades quickly in solution and isn't a common gray-market commodity at injection-grade purity.
Stop signals · abort if
- persistent severe symptoms during or after infusion (chest pain, dyspnea)
- any new arrhythmia
- persistent lab worsening
- persistent severe headache
Sources · top 5 of 60
- 01Xue X, et al. Nicotinamide adenine dinucleotide metabolism: driving or counterbalancing inflammatory bowel disease?. FEBS letters. 2023;597(9):1179-1192. PMID: 36310388.
- 02Yu F, et al. Nicotinamide Adenine Dinucleotide Supplementation to Alleviate Heart Failure: A Mitochondrial Dysfunction Perspective. Nutrients. 2025;17(11). PMID: 40507126.
- 03Bi YW, et al. Nicotinamide adenine dinucleotide phosphate oxidase in pancreatic diseases: Mechanisms and future perspectives. World journal of gastroenterology. 2024;30(5):429-439. PMID: 38414585.
- 04Navas LE, et al. Nicotinamide Adenine Dinucleotide (NAD) Metabolism as a Relevant Target in Cancer. Cells. 2022;11(17). PMID: 36078035.
- 05Shen J, et al. Nicotinamide adenine dinucleotide phosphate oxidase activation and neuronal death after ischemic stroke. Neural regeneration research. 2019;14(6):948-953. PMID: 30761998.