yes i take peptides · shopping companion
Kisspeptin-10
KP-10
Category · For WetStatus · RUOCitations · 60
The verdict
Mostly no — the only defensible use case is enrollment in a clinical trial.
By source — cost, legality, risk
- FDA-approved brandNot availableNone — no FDA approvalNo brand exists.
- Compounding pharmacy (rare)$150–$250/moOff-label Rx, rare; FDA flagged compounding concernsMid. Very few pharmacies stock it; FDA has noted concerns about kisspeptin compounding.
- RUO research-chemical site$45–$60/moSold for research onlyHighest. Dominant channel for this molecule.
- Gray-market overseas raw$3–$7/moIllegal to import for human useHighest. No purity oversight; coordination via Discord/Telegram.
Stop signals · abort if
- severe mood changes
- new menstrual irregularity
- persistent hypotension or syncope
- any new pelvic mass or breast lump
- severe headache (pituitary concern)
Sources · top 5 of 60
- 01Navarro VM. Metabolic regulation of kisspeptin - the link between energy balance and reproduction. Nature reviews. Endocrinology. 2020;16(8):407-420. PMID: 32427949.
- 02Li Z, et al. Kisspeptin-10 binding to Gpr54 in osteoclasts prevents bone loss by activating Dusp18-mediated dephosphorylation of Src. Nature communications. 2024;15(1):1300. PMID: 38346942.
- 03Aguirre RS, et al. Central precocious puberty: From genetics to treatment. Best practice & research. Clinical endocrinology & metabolism. 2018;32(4):343-354. PMID: 30086862.
- 04Colpaert T, et al. Investigating the detection of the novel doping‐relevant peptide kisspeptin‐10 in urine using liquid chromatography high‐resolution mass spectrometry. Biomedical chromatography : BMC. 2024;38(9):e5946. PMID: 38978171.
- 05Radwańska P, et al. Kisspeptin-10 increases collagen content in the myocardium by focal adhesion kinase activity. Scientific reports. 2023;13(1):19977. PMID: 37968564.