yes i take peptides · shopping companion

HMG

Human Menopausal Gonadotropin / Menotropin

Category · For WetStatus · FDACitations · 60

The verdict

Yes — but only inside a reproductive-endocrinology or men's-health clinic for documented hypogonadotropic hypogonadism or controlled ovarian stimulation. Never as a self-directed "peptide" purchased gray-market.

By source — cost, legality, risk

FDA-approved brand (Menopur, Repronex)
$80–$150 per 75iu vial · $300–$900/mo depending on protocol · $1,500+/IVF cycle
FDA-approved Rx
Lowest. Specialty fertility pharmacy; insurance variable. Hero label '$300/mo' = the low end of HH-male chronic protocol; IVF and high-frequency protocols run higher.
Compounded 503A (rare)
$250–$400/mo
Rx required; rare
Mid. Few pharmacies compound hMG — harder than hCG due to FSH/LH mix.
RUO research-chemical site
$120–$180/mo (if it were real product — which it almost never is)
Sold for research only
Highest. The molecule is purified from postmenopausal urine at industrial scale — not a synthesis route research-chemical vendors can replicate. See sourcing red flag.
Gray-market overseas raw
$85–$100/mo
Illegal to import for human use
Highest. No meaningful gray-market — hMG synthesis isn't a gray-favored route.

Sources · top 5 of 60

01Capolupo A, et al. Analytical Investigation of the Profile of Human Chorionic Gonadotropin in Highly Purified Human Menopausal Gonadotrophin Preparations. International journal of molecular sciences. 2024;25(17). PMID: 39273352.
02Li J, et al. Human menopausal gonadotropin (HMG) combined different doses of letrozole for treating anovulatory infertility in patients with polycystic ovary syndrome: a randomized controlled trial. Journal of assisted reproduction and genetics. 2025;42(6):1895-1906. PMID: 40193016.
03Li HQ, et al. Retrospective analysis: The application of human menopausal gonadotropin combined with letrozole for IUI in patients undergoing artificial insemination by husband due to unexplained or mild male factors. Frontiers in endocrinology. 2022;13:1038433. PMID: 36605946.
04Deeks ED. Highly Purified Human Menopausal Gonadotropin (Menopur(®)): A Profile of Its Use in Infertility. Clinical drug investigation. 2018;38(11):1077-1084. PMID: 30264288.
05Levi Setti PE, et al. Human recombinant follicle stimulating hormone (rFSH) compared to urinary human menopausal gonadotropin (HMG) for ovarian stimulation in assisted reproduction: a literature review and cost evaluation. Journal of endocrinological investigation. 2015;38(5):497-503. PMID: 25480425.