yes i take peptides · shopping companion

DSIP

Delta Sleep Inducing Peptide

Category · For SleepStatus · RUOCitations · 60

The verdict

No — DSIP has 50 years of mechanistic interest and almost no controlled human evidence for the sleep indication it is sold for, plus it asks an insomnia shopper to inject for a problem most insomnia shoppers expect a pill or spray to solve.

By source — cost, legality, risk

FDA-approved brand
Not available
None — no FDA approval
No brand exists.
Compounded 503A (rare)
$80–$160/mo where available
Rare — not standard 503A inventory
Hard to source legally for systemic use; very few pharmacies stock.
RUO research-chemical site
$30–$70/mo
Sold for research only
Highest. Dominant channel; identity and purity unverified.
Gray-market overseas raw
$3–$5/mo
Illegal to import for human use
Highest. Available but very small demand; DSIP rarely shows up in gray-channel discussions.

Sources · top 5 of 60

01Pollard BJ, et al. Delta sleep-inducing peptide. European journal of anaesthesiology. 2001;18(7):419-22. PMID: 11437870.
02Graf MV, et al. Delta-sleep-inducing peptide (DSIP): a review. Neuroscience and biobehavioral reviews. 1984;8(1):83-93. PMID: 6145137.
03Kovalzon VM, et al. Delta sleep-inducing peptide (DSIP): a still unresolved riddle. Journal of neurochemistry. 2006;97(2):303-9. PMID: 16539679.
04Graf MV, et al. Delta-sleep-inducing peptide (DSIP): an update. Peptides. 1986;7(6):1165-87. PMID: 3550726.
05Gimble JM, et al. Delta sleep-inducing peptide and glucocorticoid-induced leucine zipper: potential links between circadian mechanisms and obesity?. Obesity reviews : an official journal of the International Association for the Study of Obesity. 2009;10 Suppl 2:46-51. PMID: 19849801.